The new academy based at the College Green centre will offer students access to an unrivalled choice of qualifications, allowing each student to create a taylor-made curriculum that matches their personal interests.
Each student will be supported by a personal tutor who will help them prepare for university or employment.
"I'm delighted to be supporting the launch of City of Bristol College's sixth form academy. The college has a major part to play in encouraging young people to study after age 16 in Bristol," Stephen said.
"In these troubled economic times it has never been more vital to acquire new skills and qualifications. The academy will prepare young people for work and help more of them to go on to higher education."